NSight Loader

You can use this mod to inject NSight (or Renderdoc) directly without needing to use tricks like opening the launcher or running the game manually.

Slow downs and log spam are to be expected. This is due to NSight enabling the OpenGL debug context and overriding message filters.

Full instructions available here, but basically it's just plug-and-play and click on the debugger you want when the dialog pops up.

Requires x64 Windows

For injecting NSight, an NVIDIA GPU and NSight Graphics are also required.

Renderdoc should be supported on any GPU. Renderdoc is required to attach to the process (obviously).